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BRD9 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9H8M2 |
| Other Accession | NP_001009877.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 67000 Da |
| Antigen Region | 3-29 aa |
| Gene ID | 65980 |
|---|---|
| Other Names | Bromodomain-containing protein 9, Rhabdomyosarcoma antigen MU-RMS-408, BRD9 |
| Target/Specificity | This BRD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-29 amino acids from the N-terminal region of human BRD9. |
| Dilution | WB~~1:1000 IHC-P~~1:100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BRD9 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BRD9 |
|---|---|
| Function | Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA- histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058). Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed:32457312). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
BRD9 is a bromodomain containing protein, which are known to bind to acetylated lysine residues.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Scotto, L., et al. Mol. Cancer 7, 58 (2008) :
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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