|Application ||WB, E|
|Other Accession||Q9DB38, NP_001156895.1|
|Calculated MW||18756 Da|
|Antigen Region||91-119 aa|
|Other Names||Zinc finger protein 580, LDL-induced EC protein, ZNF580|
|Target/Specificity||This ZNF580 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human ZNF580.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF580 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of endothelial cell proliferation and migration. Mediates H(2)O(2)-induced leukocyte chemotaxis by elevating interleukin-8 production and may play a role in inflammation. May be involved in transcriptional regulation.|
|Cellular Location||Nucleus. Note=Colocalized with SMAD2 in the nucleus|
|Tissue Location||Expressed in endothelial cells.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF580 may be involved in transcriptional regulation.
Sun, H.Y., et al. Biochem. Biophys. Res. Commun. 395(3):361-366(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
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