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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Mouse Cdkn1b Antibody (N-term)   

Mouse Cdkn1b Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Cdkn1b Antibody (N-term) AP18599A
    Mouse Cdkn1b Antibody (N-term) (Cat. #AP18599a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Mouse Cdkn1b antibody detected the Mouse Cdkn1b protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P46414, P46527
Other Accession NP_034005.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 1-30 aa
Additional Information
Other Names Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Cdkn1b
Target/Specificity This Mouse Cdkn1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Cdkn1b.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Cdkn1b Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)

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Background

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

References

Singh, A., et al. Mol. Cell. Biol. 30(21):5145-5159(2010)
Antico-Arciuch, V.G., et al. Oncogene 29(42):5678-5686(2010)
Mitsuhashi, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16331-16335(2010)
Zhang, Y., et al. Genes Dev. 24(16):1746-1757(2010)
Wang, Y.Y., et al. J Mol Cell Biol 2(4):209-216(2010)

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Cat# AP18599A
Size:
Quantity:
(40 western blots)
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