|Application ||WB, E|
|Primary Accession||P46414, P46527|
|Antigen Region||1-30 aa|
|Other Names||Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, Cdkn1b|
|Target/Specificity||This Mouse Cdkn1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Cdkn1b.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Cdkn1b Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.
Singh, A., et al. Mol. Cell. Biol. 30(21):5145-5159(2010)
Antico-Arciuch, V.G., et al. Oncogene 29(42):5678-5686(2010)
Mitsuhashi, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16331-16335(2010)
Zhang, Y., et al. Genes Dev. 24(16):1746-1757(2010)
Wang, Y.Y., et al. J Mol Cell Biol 2(4):209-216(2010)
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