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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Kcnj11 Antibody (N-term)   

Mouse Kcnj11 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Kcnj11 Antibody (N-term) AP18601a
    Mouse Kcnj11 Antibody (N-term) (Cat. #AP18601a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Mouse Kcnj11 antibody detected the Mouse Kcnj11 protein (arrow).
  • WB - Mouse Kcnj11 Antibody (N-term) AP18601a
    Mouse Kcnj11 Antibody (N-term) (Cat. #AP18601a) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the Mouse Kcnj11 antibody detected the Mouse Kcnj11 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q61743
Other Accession O02822, Q14654, NP_034732.1
Reactivity Human, Mouse
Predicted Rabbit
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43562 Da
Antigen Region 1-27 aa
Additional Information
Gene ID 16514
Other Names ATP-sensitive inward rectifier potassium channel 11, Inward rectifier K(+) channel Kir62, Potassium channel, inwardly rectifying subfamily J member 11, Kcnj11
Target/Specificity This Mouse Kcnj11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of mouse Kcnj11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Kcnj11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Kcnj11
Function This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Background

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity).

References

Hugill, A., et al. Diabetologia 53(11):2352-2356(2010)
Li, J., et al. J. Biol. Chem. 285(37):28723-28730(2010)
Marhfour, I., et al. Cell Tissue Res. 340(2):335-346(2010)
Kurata, H.T., et al. PLoS Biol. 8 (2), E1000315 (2010) :
Alekseev, A.E., et al. Cell Metab. 11(1):58-69(2010)

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$ 295.00
$ 99.00
Cat# AP18601a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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