|Application ||WB, E|
|Other Accession||Q5SQF8, NP_001124534.1|
|Calculated MW||20877 Da|
|Antigen Region||106-134 aa|
|Other Names||Histone deacetylase complex subunit SAP30L, HCV non-structural protein 4A-transactivated protein 2, Sin3 corepressor complex subunit SAP30L, Sin3-associated protein p30-like, SAP30L, NS4ATP2|
|Target/Specificity||This SAP30L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the Central region of human SAP30L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SAP30L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus.|
|Cellular Location||Nucleus, nucleolus|
|Tissue Location||Expressed in all tissues tested with highest levels in testis|
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Provided below are standard protocols that you may find useful for product applications.
SAP30L is involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus.
Silva, L.K., et al. Eur. J. Hum. Genet. (2010) In press :
Viiri, K.M., et al. Mol. Cell. Biol. 29(2):342-356(2009)
Korkeamaki, H., et al. FEBS Lett. 582(2):379-384(2008)
Assmann, E.M., et al. J. Biol. Chem. 281(15):9869-9881(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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