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STOML1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UBI4 |
| Other Accession | Q8CI66, NP_004800.2 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42968 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 9399 |
|---|---|
| Other Names | Stomatin-like protein 1, SLP-1, EPB72-like protein 1, Protein unc-24 homolog, Stomatin-related protein, STORP, STOML1, SLP1, UNC24 |
| Target/Specificity | This STOML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human STOML1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | STOML1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STOML1 |
|---|---|
| Synonyms | SLP1, UNC24 |
| Function | May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation (PubMed:23082202). |
| Cellular Location | Membrane; Single-pass type III membrane protein. Late endosome membrane. Membrane raft. Cell membrane {ECO:0000250|UniProtKB:Q8CI66}; Single-pass type III membrane protein Cytoplasmic vesicle {ECO:0000250|UniProtKB:Q8CI66} |
| Tissue Location | Ubiquitously expressed at low levels. Expression is highest in brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
STOML1 belongs to the band 7/mec-2 family and contains one SCP2 domain. It is ubiquitously expressed at low levels; expression is highest in brain. There are two named isoforms.
References
Mairhofer, M., et al. J. Biol. Chem. 284(42):29218-29229(2009)
Gilles, F., et al. Eur. J. Haematol. 64(2):104-113(2000)
Seidel, G., et al. Gene 225 (1-2), 23-29 (1998) :
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