|Application ||WB, E|
|Calculated MW||45855 Da|
|Antigen Region||335-363 aa|
|Other Names||TBC1 domain family member 20, TBC1D20, C20orf140|
|Target/Specificity||This TBC1D20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-363 amino acids from the C-terminal region of human TBC1D20.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TBC1D20 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
TBC1D20 may act as a GTPase-activating protein for Rab family protein(s).
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Sklan, E.H., et al. J. Biol. Chem. 282(50):36354-36361(2007)
Sklan, E.H., et al. J. Virol. 81(20):11096-11105(2007)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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