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KIRREL2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6UWL6 |
| Other Accession | Q7TSU7, NP_115499.4 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 75093 Da |
| Antigen Region | 190-216 aa |
| Gene ID | 84063 |
|---|---|
| Other Names | Kin of IRRE-like protein 2, Kin of irregular chiasm-like protein 2, Nephrin-like protein 3, KIRREL2, NEPH3 |
| Target/Specificity | This KIRREL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-216 amino acids from the N-terminal region of human KIRREL2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KIRREL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KIRREL2 |
|---|---|
| Synonyms | NEPH3 |
| Function | May regulate basal insulin secretion. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q7TSU7}; Single-pass type I membrane protein. Note=Localized along the sites of the cell contacts. Colocalizes with E-Cadherin and beta- catenin. {ECO:0000250|UniProtKB:Q7TSU7} |
| Tissue Location | Highly expressed in beta-cells of the pancreatic islets. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KIRREL2 is an immunoglobulin super family gene, it has been found to be expressed in beta cells of pancreatic islets.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Ristola, M., et al. BMC Mol. Biol. 10, 83 (2009) :
Rinta-Valkama, J., et al. Diabetes Metab. Res. Rev. 23(2):119-126(2007)
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