|Application ||WB, E|
|Calculated MW||73790 Da|
|Antigen Region||193-219 aa|
|Other Names||Polycystic kidney disease 2-like 2 protein, Polycystin-2L2, Polycystin-L2, PKD2L2|
|Target/Specificity||This PKD2L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the Central region of human PKD2L2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PKD2L2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as a subunit of a cation channel and play a role in fertilization.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||According to PubMed:10602361, expressed only in testis. According to PubMed:10756092, expressed also in brain and kidney. Isoform 2 is found only in transformed lymphoblasts Isoform 3 is found in all tissues tested|
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Provided below are standard protocols that you may find useful for product applications.
PKD2L2 may function as a subunit of a cation channel and play a role in fertilization.
Li, Q., et al. FEBS Lett. 516 (1-3), 270-278 (2002) :
Stayner, C., et al. Trends Pharmacol. Sci. 22(11):543-546(2001)
Guo, L., et al. Genomics 64(3):241-251(2000)
Veldhuisen, B., et al. Eur. J. Hum. Genet. 7(8):860-872(1999)
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