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DNAJC10 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DNAJC10 Antibody (N-term) AP18675a
    DNAJC10 Antibody (N-term) (Cat. #AP18675a) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the DNAJC10 antibody detected the DNAJC10 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IXB1
Other Accession Q498R3, Q9DC23, NP_061854.1
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91080 Da
Antigen Region 56-82 aa
Additional Information
Gene ID 54431
Other Names DnaJ homolog subfamily C member 10, 184-, Endoplasmic reticulum DNA J domain-containing protein 5, ER-resident protein ERdj5, ERdj5, Macrothioredoxin, MTHr, DNAJC10, ERDJ5
Target/Specificity This DNAJC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-82 amino acids from the N-terminal region of human DNAJC10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDNAJC10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DNAJC10
Synonyms ERDJ5
Function Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
Cellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:12411443, ECO:0000269|PubMed:23769672}
Research Areas
Citations (0)

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This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. May act as a co-chaperone for HSPA5.


Wang, M., et al. J. Biol. Chem. 284(48):33377-33383(2009)
Thomas, C.G., et al. J. Biol. Chem. 284(10):6282-6290(2009)
Ushioda, R., et al. Science 321(5888):569-572(2008)
Dong, M., et al. Mol. Biol. Cell 19(6):2620-2630(2008)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)

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$ 295.00
$ 99.00
Cat# AP18675a
(40 western blots)
Availability: In Stock
Bulk Size
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