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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TREML1 Antibody (C-term)   

TREML1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TREML1 Antibody (C-term) AP18683B
    TREML1 Antibody (C-term) (Cat. #AP18683b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).
  • WB - TREML1 Antibody (C-term) AP18683B
    TREML1 Antibody (C-term) (Cat. #AP18683b) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the TREML1 antibody detected the TREML1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86YW5
Other Accession NP_835468.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32679 Da
Antigen Region 215-241 aa
Additional Information
Gene ID 340205
Other Names Trem-like transcript 1 protein, TLT-1, Triggering receptor expressed on myeloid cells-like protein 1, TREML1, TLT1
Target/Specificity This TREML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-241 amino acids from the C-terminal region of human TREML1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTREML1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TLT1
Function Cell surface receptor that may play a role in the innate and adaptive immune response.
Cellular Location Cell membrane; Single-pass type I membrane protein Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151) Transported to the cell surface after stimulation by thrombin (PubMed:15100151). Soluble fragments can be released into the serum by proteolysis (PubMed:16505478)
Tissue Location Detected in platelets, monocytic leukemia and in T-cell leukemia.
Research Areas
Citations (0)

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TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM].


Morales, J., et al. Blood Coagul. Fibrinolysis 21(3):229-236(2010)
Washington, A.V., et al. J. Clin. Invest. 119(6):1489-1501(2009)
Ford, J.W., et al. Curr. Opin. Immunol. 21(1):38-46(2009)
Nurden, A.T., et al. Thromb. Haemost. 100(1):45-51(2008)
Giomarelli, B., et al. Thromb. Haemost. 97(6):955-963(2007)

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$ 295.00
$ 99.00
Cat# AP18683B
(40 western blots)
Availability: In Stock
Bulk Size
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