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VCX3A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NNX9 |
| Other Accession | Q9H322, Q9H320, NP_057463.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20020 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 51481 |
|---|---|
| Other Names | Variable charge X-linked protein 3, Variable charge protein on X with eight repeats, VCX-8r, Variably charged protein X-A, VCX-A, VCX3A, VCX3, VCX8R, VCXA |
| Target/Specificity | This VCX3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human VCX3A. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | VCX3A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | VCX3A |
|---|---|
| Synonyms | VCX3, VCX8R, VCXA |
| Function | May mediate a process in spermatogenesis or may play a role in sex ratio distortion. |
| Tissue Location | Expressed exclusively in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq].
References
Jiao, X., et al. J. Neurosci. 29(40):12419-12427(2009)
Cuevas-Covarrubias, S.A., et al. Br. J. Dermatol. 158(3):483-486(2008)
Jiao, X., et al. Mol. Cell 24(5):713-722(2006)
Fukami, M., et al. Am. J. Hum. Genet. 67(3):563-573(2000)
Lahn, B.T., et al. Hum. Mol. Genet. 9(2):311-319(2000)
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