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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Rab17 Antibody (Center)   

Mouse Rab17 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Rab17 Antibody (Center) AP18691C
    Mouse Rab17 Antibody (Center) (Cat. #AP18691c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Mouse Rab17 antibody detected the Mouse Rab17 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35292
Other Accession NP_001153197.2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23640 Da
Antigen Region 83-110 aa
Additional Information
Gene ID 19329
Other Names Ras-related protein Rab-17, Rab17
Target/Specificity This Mouse Rab17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-110 amino acids from the Central region of mouse Rab17.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Rab17 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rab17
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post- endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development. May also play a role in cell migration.
Cellular Location Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendrite. Note=According to a report the protein is localized at the basolateral and apical plasma membrane of kidney epithelial cells (PubMed:8486736). It was later shown to localize to the apical recycling endosome in epithelial cells (PubMed:21291502). In neurons, localizes to the cell body and dendritic shaft and spine
Tissue Location Expressed in kidney, liver, and intestine mainly by epithelial cells. Expressed in hippocampus (at protein level).
Research Areas
Citations (0)

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Rab17 might be involved in transcellular transport.


Itoh, T., et al. Genes Cells 11(9):1023-1037(2006)
Fukuda, M. J. Biol. Chem. 278(17):15373-15380(2003)
Fukuda, M., et al. J. Biol. Chem. 277(14):12432-12436(2002)
Kuroda, T.S., et al. J. Biol. Chem. 277(11):9212-9218(2002)
Lehtonen, S., et al. Int. J. Dev. Biol. 43(5):425-433(1999)

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$ 295.00
$ 99.00
Cat# AP18691C
(40 western blots)
Availability: In Stock
Bulk Size
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