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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HAS3 Antibody (Center)   

HAS3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HAS3 Antibody (Center) AP18700c
    HAS3 Antibody (Center) (Cat. #AP18700c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HAS3 antibody detected the HAS3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00219
Other Accession O08650, NP_005320.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 62998 Da
Antigen Region 137-164 aa
Additional Information
Gene ID 3038
Other Names Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3, HAS3
Target/Specificity This HAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human HAS3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHAS3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HAS3
Function Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity).
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.


Dunn, K.M., et al. Surgery 145(3):322-329(2009)
Nykopp, T.K., et al. BMC Cancer 9, 143 (2009) :
Nair, S., et al. J. Nephrol. 21(3):400-405(2008)
Campo, G.M., et al. Mol. Cell. Biochem. 292 (1-2), 169-178 (2006) :
Grskovic, B., et al. Biochim. Biophys. Acta 1760(6):890-895(2006)

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$ 295.00
$ 99.00
Cat# AP18700c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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