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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OLIG2 Antibody (Center)   

OLIG2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OLIG2 Antibody (Center) AP18701C
    OLIG2 Antibody (Center) (Cat. #AP18701c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OLIG2 antibody detected the OLIG2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13516
Other Accession Q9EQW6, Q90XB3, NP_005797.1
Reactivity Mouse
Predicted Chicken
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32385 Da
Antigen Region 152-180 aa
Additional Information
Gene ID 10215
Other Names Oligodendrocyte transcription factor 2, Oligo2, Class B basic helix-loop-helix protein 1, bHLHb1, Class E basic helix-loop-helix protein 19, bHLHe19, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, OLIG2, BHLHB1, BHLHE19, PRKCBP2, RACK17
Target/Specificity This OLIG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human OLIG2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOLIG2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OLIG2
Function Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}. Cytoplasm. Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2
Tissue Location Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Research Areas
Citations (0)

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This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq].


Durand, K.S., et al. Mod. Pathol. 23(4):619-628(2010)
Sims, R., et al. Neurosci. Lett. 461(1):54-59(2009)
Hwang, D.H., et al. BMC Neurosci 10, 117 (2009) :
Ishizawa, K., et al. Clin. Neuropathol. 27(3):118-128(2008)
Ahn, S.M., et al. PLoS ONE 3 (12), E3917 (2008) :

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$ 295.00
$ 99.00
Cat# AP18701C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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