|Application ||WB, E|
|Calculated MW||80245 Da|
|Antigen Region||84-113 aa|
|Other Names||Kelch-like protein 4, KLHL4, KIAA1687|
|Target/Specificity||This KLHL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the N-terminal region of human KLHL4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLHL4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm, cytoskeleton.|
|Tissue Location||Expressed in adult fibroblasts and in a range of fetal tissues including tongue, palate, and mandible|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Styrkarsdottir, U., et al. Nat. Genet. 41(1):15-17(2009)
Cheroki, C., et al. J. Med. Genet. 45(4):228-232(2008)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Braybrook, C., et al. Hum. Genet. 108(6):537-545(2001)
Braybrook, C., et al. Genomics 72(2):128-136(2001)
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