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SUGT1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y2Z0 |
| Other Accession | B0BN85, Q9CX34, Q2KIK0, NP_001124384.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41024 Da |
| Antigen Region | 330-356 aa |
| Gene ID | 10910 |
|---|---|
| Other Names | Suppressor of G2 allele of SKP1 homolog, Protein 40-6-3, Sgt1, SUGT1 |
| Target/Specificity | This SUGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-356 amino acids from the C-terminal region of human SUGT1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SUGT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SUGT1 (HGNC:16987) |
|---|---|
| Function | May play a role in ubiquitination and subsequent proteasomal degradation of target proteins. |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocates to the nucleus upon heat shock, requiring S100A6 |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene.
References
Davies, A.E., et al. J. Cell Biol. 189(2):261-274(2010)
Iwatsuki, M., et al. Int. J. Oncol. 36(3):569-575(2010)
Bansal, P.K., et al. J. Biol. Chem. 284(28):18692-18698(2009)
Zabka, M., et al. Biochem. Biophys. Res. Commun. 370(1):179-183(2008)
Spiechowicz, M., et al. Biochem. Biophys. Res. Commun. 357(4):1148-1153(2007)
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