|Application ||WB, E|
|Other Accession||O54818, NP_001003395.1|
|Calculated MW||22449 Da|
|Antigen Region||43-70 aa|
|Other Names||Tumor protein D53, hD53, Tumor protein D52-like 1, TPD52L1|
|Target/Specificity||This TPD52L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human TPD52L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TPD52L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined.
Barbaric, D., et al. Leuk. Res. 30(11):1355-1363(2006)
Cao, Q., et al. Biochem. Biophys. Res. Commun. 344(3):798-806(2006)
Boutros, R., et al. Exp. Cell Res. 310(1):152-165(2005)
Cho, S., et al. J. Biol. Chem. 279(16):16050-16056(2004)
Boutros, R., et al. J. Mol. Biol. 332(3):675-687(2003)
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