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AGPAT5 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NUQ2 |
| Other Accession | NP_060831.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 42072 Da |
| Antigen Region | 28-55 aa |
| Gene ID | 55326 |
|---|---|
| Other Names | 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5, 1-AGP acyltransferase 5, 1-AGPAT 5, Lysophosphatidic acid acyltransferase epsilon, LPAAT-epsilon, AGPAT5 |
| Target/Specificity | This AGPAT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human AGPAT5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AGPAT5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AGPAT5 |
|---|---|
| Function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor (PubMed:21173190). Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl- CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA (PubMed:21173190). Activity toward lysophosphatidylglycerol not detectable (PubMed:21173190). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope Mitochondrion |
| Tissue Location | Widely expressed. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Agarwal, A.K., et al. Arch. Biochem. Biophys. 449 (1-2), 64-76 (2006) :
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Lu, B., et al. Biochem. J. 385 (PT 2), 469-477 (2005) :
Leung, D.W. Front. Biosci. 6, D944-D953 (2001) :
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