|Application ||WB, E|
|Calculated MW||29971 Da|
|Antigen Region||70-98 aa|
|Other Names||Calcium-activated chloride channel regulator family member 3, Calcium-activated chloride channel family member 3, hCLCA3, CLCA3P, CLCA3|
|Target/Specificity||This CLCA3P antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the Central region of human CLCA3P.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CLCA3P Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in the lung, trachea, spleen, thymus and mammary gland.|
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mCLCA3 (alias gob-5) is the third murine member of the family of calcium-activated chloride channels (CLCA-family). mCLCA3 plays a role in diseases with secretory dysfunctions, including asthma and cystic fibrosis. The mCLCA3 protein is located in mucin granule membranes of goblet cells of the intestinal, respiratory and reproductive tracts. It is also secreted into the mucin layer on mucosal membranes. The protein appears to be involved in the synthesis, condensation or secretion of mucins.
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