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DMWD Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q09019 |
| Other Accession | Q08274, NP_004934.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70438 Da |
| Antigen Region | 519-545 aa |
| Gene ID | 1762 |
|---|---|
| Other Names | Dystrophia myotonica WD repeat-containing protein, Dystrophia myotonica-containing WD repeat motif protein, Protein 59, Protein DMR-N9, DMWD, DM9 |
| Target/Specificity | This DMWD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-545 amino acids from the C-terminal region of human DMWD. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DMWD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DMWD (HGNC:2936) |
|---|---|
| Synonyms | DM9 |
| Function | Regulator of the deubiquitinating USP12/DMWD/WDR48 complex (PubMed:33844468). Functions as a cofactor that promotes USP12 enzymatic activity (PubMed:33844468). |
| Cellular Location | Cytoplasm. Nucleus. Perikaryon {ECO:0000250|UniProtKB:Q08274}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q08274}. Note=Localizes mainly to the cytoplasm however shuttles between the cytoplasm and nucleus (PubMed:33844468) In neurons, shows punctate expression throughout the cell body, nucleus and dendrites. Not detected in axons. {ECO:0000250|UniProtKB:Q08274, ECO:0000269|PubMed:33844468} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
DMWD could have a regulatory function in meiosis.
References
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Wansink, D.G., et al. Cytogenet. Genome Res. 100 (1-4), 230-242 (2003) :
Eriksson, M., et al. Biochem. Biophys. Res. Commun. 286(5):1177-1182(2001)
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