|Application ||WB, E|
|Calculated MW||33893 Da|
|Antigen Region||177-204 aa|
|Other Names||Deoxyribonuclease-1-like 1, 3121-, DNase X, Deoxyribonuclease I-like 1, DNase I-like 1, Muscle-specific DNase I-like, XIB, DNASE1L1, DNAS1L1, DNL1L|
|Target/Specificity||This DNASE1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-204 amino acids from the Central region of human DNASE1L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNASE1L1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum|
|Tissue Location||Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Bailey, S.D., et al. Diabetes Care (2010) In press :
Ueki, M., et al. Electrophoresis 31(12):2063-2069(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Shiokawa, D., et al. Biochem. J. 392 (PT 3), 511-517 (2005) :
Malferrari, G., et al. Exp. Mol. Pathol. 66(2):123-130(1999)
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