|Application ||WB, E|
|Other Accession||Q68FM6, Q5R3F8, Q8C8T7|
|Calculated MW||90477 Da|
|Antigen Region||766-792 aa|
|Other Names||Protein ELFN1, Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1, Protein phosphatase 1 regulatory subunit 28, ELFN1, PPP1R28|
|Target/Specificity||This ELFN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 766-792 amino acids from the C-terminal region of human ELFN1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ELFN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.|
|Cellular Location||Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localizes to excitatory synapses onto somatostatin (Sst)-containing oriens-lacunosum moleculare (O-LM) interneurons.|
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The function of this protein remains unknown.
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