ELFN1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P0C7U0 |
Other Accession | Q68FM6, Q5R3F8, Q8C8T7 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 90477 Da |
Antigen Region | 766-792 aa |
Gene ID | 392617 |
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Other Names | Protein ELFN1, Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1, Protein phosphatase 1 regulatory subunit 28, ELFN1, PPP1R28 |
Target/Specificity | This ELFN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 766-792 amino acids from the C-terminal region of human ELFN1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ELFN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ELFN1 |
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Synonyms | PPP1R28 |
Function | Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. |
Cellular Location | Membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Localizes to excitatory synapses onto somatostatin (Sst)-containing oriens-lacunosum moleculare (O-LM) interneurons |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
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