|Application ||WB, E|
|Other Accession||Q08850, P70452, Q3SWZ3, NP_004595.2|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||34180 Da|
|Antigen Region||132-160 aa|
|Other Names||Syntaxin-4, Renal carcinoma antigen NY-REN-31, STX4, STX4A|
|Target/Specificity||This STX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of human STX4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STX4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.|
|Cellular Location||Cell membrane; Single-pass type IV membrane protein|
|Tissue Location||Expressed in neutrophils and neutrophil- differentiated HL-60 cells. Expression in neutrophils increases with differentiation.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Evesson, F.J., et al. J. Biol. Chem. 285(37):28529-28539(2010)
Kennedy, M.J., et al. Cell 141(3):524-535(2010)
Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)
Cooper, G.M., et al. Blood 112(4):1022-1027(2008)
Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.