|Application ||WB, E|
|Other Accession||Q5FWK3, NP_004299.1|
|Calculated MW||50436 Da|
|Antigen Region||126-154 aa|
|Other Names||Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP, ARHGAP1, CDC42GAP, RHOGAP1|
|Target/Specificity||This ARHGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human ARHGAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARHGAP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
Mori, K., et al. J. Biol. Chem. 284(8):5067-5076(2009)
Scholz, R.P., et al. J. Cell. Sci. 122 (PT 1), 92-102 (2009) :
Budanova, E.N., et al. Genetika 44(2):170-176(2008)
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