|Application ||WB, E|
|Other Accession||Q5FWK3, NP_004299.1|
|Calculated MW||50436 Da|
|Antigen Region||126-154 aa|
|Other Names||Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP, ARHGAP1, CDC42GAP, RHOGAP1|
|Target/Specificity||This ARHGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human ARHGAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARHGAP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.|
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Provided below are standard protocols that you may find useful for product applications.
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
Mori, K., et al. J. Biol. Chem. 284(8):5067-5076(2009)
Scholz, R.P., et al. J. Cell. Sci. 122 (PT 1), 92-102 (2009) :
Budanova, E.N., et al. Genetika 44(2):170-176(2008)
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