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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   OSCAR Antibody (C-term)   

OSCAR Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OSCAR Antibody (C-term) AP18846b
    OSCAR Antibody (C-term)(Cat. #AP18846b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the OSCAR antibody detected the OSCAR protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IYS5
Other Accession NP_570127.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30481 Da
Antigen Region 205-231 aa
Additional Information
Gene ID 126014
Other Names Osteoclast-associated immunoglobulin-like receptor, Osteoclast-associated receptor, hOSCAR, Polymeric immunoglobulin receptor 3, PIgR-3, PIgR3, Poly-Ig receptor 3, OSCAR
Target/Specificity This OSCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human OSCAR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOSCAR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
Cellular Location Isoform 1: Secreted.
Research Areas
Citations (0)

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Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Herman, S., et al. Arthritis Rheum. 58(10):3041-3050(2008)
Merck, E., et al. J. Immunol. 176(5):3149-3156(2006)
Kim, K., et al. J. Biol. Chem. 280(42):35209-35216(2005)

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$ 295.00
$ 99.00
Cat# AP18846b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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