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>   home   >   Products   >   Primary Antibodies   >   PRICKLE1 Antibody (C-term)   

PRICKLE1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRICKLE1 Antibody (C-term) AP18864B
    PRICKLE1 Antibody (C-term)(Cat. #AP18864b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRICKLE1 antibody detected the PRICKLE1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96MT3
Other Accession NP_001138353.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 94300 Da
Antigen Region 678-704 aa
Additional Information
Gene ID 144165
Other Names Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1, PRICKLE1, RILP
Target/Specificity This PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 678-704 amino acids from the C-terminal region of human PRICKLE1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRICKLE1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RILP
Function Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
Cellular Location Nucleus membrane. Cytoplasm, cytosol. Note=A smaller amount is detected in the cytosol
Tissue Location Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia).
Citations (0)

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This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.


Smith, N.L., et al. Circ Cardiovasc Genet 3(3):256-266(2010)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Perry, J.R., et al. Diabetes 58(6):1463-1467(2009)
Narimatsu, M., et al. Cell 137(2):295-307(2009)
Shimojo, M. J. Biol. Chem. 283(50):34880-34886(2008)

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$ 295.00
$ 99.00
Cat# AP18864B
(40 western blots)
Availability: In Stock
Bulk Size
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