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PTPLAD1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTPLAD1 Antibody (N-term) AP18866a
    PTPLAD1 Antibody (N-term)(Cat. #AP18866a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PTPLAD1 antibody detected the PTPLAD1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P035
Other Accession Q8K2C9, A7YY55, NP_057479.2
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43160 Da
Antigen Region 32-58 aa
Additional Information
Gene ID 51495
Other Names Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3, 3-hydroxyacyl-CoA dehydratase 3, HACD3, Butyrate-induced protein 1, B-ind1, hB-ind1, Protein tyrosine phosphatase-like protein PTPLAD1, Protein-tyrosine phosphatase-like A domain-containing protein 1, PTPLAD1, BIND1, HACD3
Target/Specificity This PTPLAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-58 amino acids from the N-terminal region of human PTPLAD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPLAD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HACD3 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:24175}
Function Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Highly expressed in testis, kidney, brain, liver and weakly in skeletal muscle, spleen and heart. No expression detected in leukocytes.
Research Areas
Citations (0)

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Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis. Involved in Rac1-signaling pathways leading to the modulation of gene expression.


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Taguwa, S., et al. J. Virol. 83(20):10427-10436(2009)
Taguwa, S., et al. J. Virol. 82(6):2631-2641(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Sabbah, M., et al. Gene 374, 128-133 (2006) :

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$ 295.00
$ 99.00
Cat# AP18866a
(40 western blots)
Availability: In Stock
Bulk Size
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