|Application ||WB, E|
|Other Accession||Q5F413, Q91VZ6, NP_001037770.1|
|Calculated MW||50386 Da|
|Antigen Region||87-113 aa|
|Other Names||Stromal membrane-associated protein 1, SMAP1|
|Target/Specificity||This SMAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-113 amino acids from the N-terminal region of human SMAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SMAP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis (By similarity).|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Detected in bone marrow, adrenal gland, trachea, lymph node, spinal cord, peripheral blood leukocytes, thyroid and stomach.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms.
Barragan, I., et al. Int. J. Mol. Med. 16(6):1163-1167(2005)
Tanabe, K., et al. Mol. Biol. Cell 16(4):1617-1628(2005)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Marcos, I., et al. Gene 292 (1-2), 167-171 (2002) :
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