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TARM1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | B6A8C7 |
| Other Accession | NP_001129158.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29455 Da |
| Antigen Region | 243-270 aa |
| Gene ID | 441864 |
|---|---|
| Other Names | T-cell-interacting, activating receptor on myeloid cells protein 1, OSCAR-like transcript-2 protein, OLT-2, TARM1 |
| Target/Specificity | This TARM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-270 amino acids from the C-terminal region of human TARM1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TARM1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TARM1 |
|---|---|
| Function | May act as receptor (By similarity). Negatively regulates TCR-mediated CD4(+) T cell proliferation and activation, possibly by binding an unknown ligand on the T cell surface (PubMed:26311901). Enhances Toll-like receptor-mediated production of pro-inflammatory cytokines by macrophages and neutrophils (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed in fetal and adult liver, lung, testis, thymus and spleen. Expressed in blood neutrophils |
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein remains unknown.
References
Kohn, L., et al. Eur. J. Hum. Genet. 17(5):651-655(2009)
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