|Application ||WB, E|
|Other Accession||Q5BK32, Q3TDN2, Q2HJD0, NP_055428.1|
|Calculated MW||52623 Da|
|Antigen Region||348-377 aa|
|Other Names||FAS-associated factor 2, Protein ETEA, UBX domain-containing protein 3B, UBX domain-containing protein 8, FAF2, ETEA, KIAA0887, UBXD8, UBXN3B|
|Target/Specificity||This FAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-377 amino acids from the C-terminal region of human FAF2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAF2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ETEA, KIAA0887, UBXD8, UBXN3B|
|Function||May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.|
|Cellular Location||Cytoplasm. Lipid droplet. Endoplasmic reticulum|
|Tissue Location||Broadly expressed, with highest levels in brain.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients.
Phan, V.T., et al. Mol. Cell. Biol. 30(9):2264-2279(2010)
Ernst, R., et al. Mol. Cell 36(1):28-38(2009)
Alexandru, G., et al. Cell 134(5):804-816(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Imai, Y., et al. Biochem. Biophys. Res. Commun. 297(5):1282-1290(2002)
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