|Application ||WB, E|
|Other Accession||Q3TY92, NP_443129.3|
|Calculated MW||101201 Da|
|Antigen Region||977-1003 aa|
|Other Names||Methyl-CpG-binding domain protein 6, Methyl-CpG-binding protein MBD6, MBD6, KIAA1887|
|Target/Specificity||This MBD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 977-1003 amino acids from the C-terminal region of human MBD6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MBD6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro).|
|Cellular Location||Nucleus. Chromosome. Note=Associated with pericentric heterochromatin in about 25% of the cells|
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Provided below are standard protocols that you may find useful for product applications.
Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro).
Laget, S., et al. PLoS ONE 5 (8), E11982 (2010) :
Roloff, T.C., et al. BMC Genomics 4 (1), 1 (2003) :
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