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GAS2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GAS2 Antibody (N-term) AP18918A
    GAS2 Antibody (N-term) (Cat. #AP18918a) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GAS2 antibody detected the GAS2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43903
Other Accession NP_001137302.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34945 Da
Antigen Region 68-94 aa
Additional Information
Gene ID 2620
Other Names Growth arrest-specific protein 2, GAS-2, GAS2
Target/Specificity This GAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-94 amino acids from the N-terminal region of human GAS2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGAS2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAS2
Function May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).
Cellular Location Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth- arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity).
Tissue Location Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen
Research Areas
Citations (0)

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The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.


Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Benetti, R., et al. J. Biol. Chem. 280(23):22070-22080(2005)
Tsutsumi, S., et al. Am. J. Hum. Genet. 74(6):1255-1261(2004)
Benetti, R., et al. EMBO J. 20(11):2702-2714(2001)

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$ 295.00
$ 99.00
Cat# AP18918A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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