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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COPB2 Antibody (C-term)   

COPB2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - COPB2 Antibody (C-term) AP18930b
    COPB2 Antibody (C-term) (Cat. #AP18930b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the COPB2 antibody detected the COPB2 protein (arrow).
  • WB - COPB2 Antibody (C-term) AP18930b
    COPB2 Antibody (C-term) (Cat. #AP18930b) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the COPB2 antibody detected the COPB2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35606
Other Accession NP_004757.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 102487 Da
Antigen Region 814-843 aa
Additional Information
Gene ID 9276
Other Names Coatomer subunit beta', Beta'-coat protein, Beta'-COP, p102, COPB2
Target/Specificity This COPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 814-843 amino acids from the C-terminal region of human COPB2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOPB2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COPB2
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Cellular Location Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows only a slight preference for the cis-Golgi apparatus, compared with the trans-Golgi.
Research Areas
Citations (0)

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The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.


Kim, E., et al. Biochem. Biophys. Res. Commun. 395(2):244-250(2010)
Guo, Y., et al. Mol. Biol. Cell 19(7):2830-2843(2008)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 295.00
$ 99.00
Cat# AP18930b
(40 western blots)
Availability: In Stock
Bulk Size
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