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ZBTB17 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZBTB17 Antibody (N-term) AP18958a
    ZBTB17 Antibody (N-term) (Cat. #AP18958a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ZBTB17 antibody detected the ZBTB17 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13105
Other Accession NP_003434.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 87928 Da
Antigen Region 113-142 aa
Additional Information
Gene ID 7709
Other Names Zinc finger and BTB domain-containing protein 17, Myc-interacting zinc finger protein 1, Miz-1, Zinc finger protein 151, Zinc finger protein 60, ZBTB17, MIZ1, ZNF151, ZNF60
Target/Specificity This ZBTB17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human ZBTB17.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZBTB17 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB17
Synonyms MIZ1, ZNF151, ZNF60
Function Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. Represses RB1 transcription; this repression can be blocked by interaction with ZBTB49 isoform 3/ZNF509S1 (PubMed:25245946).
Cellular Location Nucleus
Tissue Location Expressed in germinal center B-cells.
Research Areas
Citations (0)

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This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq].


Licchesi, J.D., et al. Oncogene 29(44):5923-5934(2010)
Miao, L., et al. Oncogene 29(5):711-722(2010)
Liu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(43):18279-18284(2009)
Basu, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(5):1433-1438(2009)
Ikegaki, N., et al. Clin. Cancer Res. 13(20):6001-6009(2007)

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$ 295.00
$ 99.00
Cat# AP18958a
(40 western blots)
Availability: In Stock
Bulk Size
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