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KCTD17 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - KCTD17 Antibody (Center) AP18982c
    KCTD17 Antibody (Center) (Cat. #AP18982c) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KCTD17 antibody detected the KCTD17 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N5Z5
Other Accession NP_078957.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35670 Da
Antigen Region 107-136 aa
Additional Information
Gene ID 79734
Other Names BTB/POZ domain-containing protein KCTD17, KCTD17
Target/Specificity This KCTD17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-136 amino acids from the Central region of human KCTD17.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCTD17 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCTD17
Function Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).
Cellular Location Cytoplasm.
Tissue Location Highly expressed in brain. Highest expression is observed in the putamen and the thalamus
Research Areas
Citations (0)

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Background

The function of this protein remains unknown.

References

Dunham, I., et al. Nature 402(6761):489-495(1999)

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$ 295.00
$ 99.00
Cat# AP18982c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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