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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TRIM58 Antibody (C-term)   

TRIM58 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRIM58 Antibody (C-term) AP18986b
    TRIM58 Antibody (C-term) (Cat. #AP18986b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TRIM58 antibody detected the TRIM58 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NG06
Other Accession NP_056246.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54766 Da
Antigen Region 457-486 aa
Additional Information
Gene ID 25893
Other Names E3 ubiquitin-protein ligase TRIM58, 632-, Protein BIA2, Tripartite motif-containing protein 58, TRIM58
Target/Specificity This TRIM58 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the C-terminal region of human TRIM58.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRIM58 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM58
Function E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization.
Tissue Location Expressed in erythroblasts.
Research Areas
Citations (0)

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TRIM58 belongs to the TRIM/RBCC family of proteins. it contains a B box-type zinc finger domain, a B30.2/SPRY domain and a RING-type zinc finger domian.


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)

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$ 295.00
$ 99.00
Cat# AP18986b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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