|Application ||WB, E|
|Calculated MW||80700 Da|
|Antigen Region||293-322 aa|
|Other Names||Prolyl endopeptidase, PE, Post-proline cleaving enzyme, PREP, PEP|
|Target/Specificity||This PREP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-322 amino acids from the Central region of human PREP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PREP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides.
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Tenorio-Laranga, J., et al. J Neuroinflammation 7, 23 (2010) :
Pillas, D., et al. PLoS Genet. 6 (2), E1000856 (2010) :
Malhotra, A., et al. Diabetes Metab. Res. Rev. 25(8):740-747(2009)
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