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RASA3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RASA3 Antibody (C-term) AP19031b
    RASA3 Antibody (C-term) (Cat. #AP19031b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the RASA3 antibody detected the RASA3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14644
Other Accession NP_031394.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 95699 Da
Antigen Region 594-623 aa
Additional Information
Gene ID 22821
Other Names Ras GTPase-activating protein 3, GAP1(IP4BP), Ins P4-binding protein, RASA3
Target/Specificity This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRASA3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RASA3
Function Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
Cellular Location Cell membrane.
Research Areas
Citations (0)

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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.


Kupzig, S., et al. Mol. Cell. Biol. 29(14):3929-3940(2009)
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Walker, S.A., et al. J. Biol. Chem. 277(50):48779-48785(2002)
Koehler, J.A., et al. Biochem. Biophys. Res. Commun. 283(4):888-895(2001)
Cozier, G.E., et al. J. Biol. Chem. 275(36):28261-28268(2000)

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$ 295.00
$ 99.00
Cat# AP19031b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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