|Application ||WB, E|
|Other Accession||P56183, NP_003674.1|
|Calculated MW||52839 Da|
|Antigen Region||298-326 aa|
|Other Names||Ribosomal RNA processing protein 1 homolog A, Novel nuclear protein 1, NNP-1, Nucleolar protein Nop52, RRP1-like protein, RRP1, D21S2056E, NNP1, NOP52, RRP1A|
|Target/Specificity||This RRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human RRP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RRP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||D21S2056E, NNP1, NOP52, RRP1A|
|Function||Plays a critical role in the generation of 28S rRNA.|
|Cellular Location||Nucleus, nucleolus|
|Tissue Location||Ubiquitously expressed in fetal and adult tissues.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA.
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)
Behrends, U., et al. Int. J. Cancer 100(6):669-677(2002)
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