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ZNF326 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ZNF326 Antibody (N-term) AP19060A
    ZNF326 Antibody (N-term) (Cat. #AP19060a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ZNF326 antibody detected the ZNF326 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q5BKZ1
Other Accession O88291, F1MJM0, NP_892021.1
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 65654 Da
Antigen Region 127-155 aa
Additional Information
Gene ID 284695
Other Names DBIRD complex subunit ZNF326, Zinc finger protein 326, Zinc finger protein interacting with mRNPs and DBC1, ZNF326, ZIRD
Target/Specificity This ZNF326 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the N-terminal region of human ZNF326.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZNF326 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF326
Synonyms ZIRD
Function Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro.
Cellular Location Nucleus matrix.
Research Areas
Citations (0)
citation

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Background

Probable transcriptional activator which may play a role in neuronal differentiation. Able to bind DNA and activate expression in vitro (By similarity).

References

O'Donnell, C.J., et al. BMC Med. Genet. 8 SUPPL 1, S4 (2007) :
Andersen, J.S., et al. Nature 433(7021):77-83(2005)

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$ 182.50
$ 70.00
Cat# AP19060A
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