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GKN1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NS71 |
| Other Accession | NP_062563.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20331 Da |
| Antigen Region | 124-150 aa |
| Gene ID | 56287 |
|---|---|
| Other Names | Gastrokine-1, 18 kDa antrum mucosa protein, AMP-18, Protein CA11, GKN1, AMP18, CA11 |
| Target/Specificity | This GKN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-150 amino acids from the C-terminal region of human GKN1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GKN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GKN1 |
|---|---|
| Synonyms | AMP18, CA11 |
| Function | Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. |
| Cellular Location | Secreted. Cytoplasmic granule. Golgi apparatus. Note=Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. |
| Tissue Location | Expressed in stomach (at protein level). No expression is detected in cancer tissue or gastric cancer cell lines |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Broderick, P., et al. Cancer Res. 69(16):6633-6641(2009)
Nardone, G., et al. Cancer Biol. Ther. 7(12):1890-1895(2008)
Moss, S.F., et al. Clin. Cancer Res. 14(13):4161-4167(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
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