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SPANXE Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPANXE Antibody (Center) AP19072c
    SPANXE Antibody (Center) (Cat. #AP19072c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SPANXE antibody detected the SPANXE protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TAD1
Other Accession Q9NY87, Q9NS25, NP_663698.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 10982 Da
Antigen Region 39-65 aa
Additional Information
Gene ID 64663
Other Names Sperm protein associated with the nucleus on the X chromosome E, Nuclear-associated protein SPAN-Xe, SPANX-E, SPANX family member E, SPANXE
Target/Specificity This SPANXE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of human SPANXE.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPANXE Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Cellular Location Cytoplasm. Nucleus. Note=Associated with nuclear craters
Tissue Location Detected in testis, sperm and a melanoma cell line.
Citations (0)

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Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that contains a consensus nuclear localization signal but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined.


Hansen, S., et al. Syst Biol Reprod Med 55, 18-26 (2010) :
Kouprina, N., et al. Genome Res. 15(11):1477-1486(2005)
Zendman, A.J., et al. Gene 309(2):125-133(2003)
Westbrook, V.A., et al. Biol. Reprod. 64(1):345-358(2001)

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Cat# AP19072c
(40 western blots)
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