|Application ||WB, E|
|Calculated MW||35915 Da|
|Antigen Region||287-313 aa|
|Other Names||Taste receptor type 2 member 3, T2R3, TAS2R3|
|Target/Specificity||This TAS2R3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-313 amino acids from the C-terminal region of human TAS2R3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TAS2R3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception.
Calvo, S.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(18):7507-7512(2009)
Go, Y., et al. Genetics 170(1):313-326(2005)
Fischer, A., et al. Mol. Biol. Evol. 22(3):432-436(2005)
Zhang, Y., et al. Cell 112(3):293-301(2003)
Montmayeur, J.P., et al. Curr. Opin. Neurobiol. 12(4):366-371(2002)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.