|Application ||WB, E|
|Other Accession||P58802, NP_114143.1|
|Calculated MW||57118 Da|
|Antigen Region||239-267 aa|
|Other Names||TBC1 domain family member 10A, EBP50-PDX interactor of 64 kDa, EPI64 protein, Rab27A-GAP-alpha, TBC1D10A, EPI64, TBC1D10|
|Target/Specificity||This TBC1D10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human TBC1D10A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TBC1D10A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.|
|Cellular Location||Cell projection, microvillus. Note=Localizes to the microvilli- rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells|
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Provided below are standard protocols that you may find useful for product applications.
TBC1D10A acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.
Gao, Y., et al. J. Biol. Chem. 285(23):17938-17953(2010)
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Patino-Lopez, G., et al. J. Biol. Chem. 283(26):18323-18330(2008)
Hanono, A., et al. J. Cell Biol. 175(5):803-813(2006)
Itoh, T., et al. J. Biol. Chem. 281(42):31823-31831(2006)
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