|Application ||WB, E|
|Other Accession||P58802, NP_114143.1|
|Calculated MW||57118 Da|
|Antigen Region||239-267 aa|
|Other Names||TBC1 domain family member 10A, EBP50-PDX interactor of 64 kDa, EPI64 protein, Rab27A-GAP-alpha, TBC1D10A, EPI64, TBC1D10|
|Target/Specificity||This TBC1D10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human TBC1D10A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TBC1D10A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.|
|Cellular Location||Cell projection, microvillus. Note=Localizes to the microvilli- rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
TBC1D10A acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A.
Gao, Y., et al. J. Biol. Chem. 285(23):17938-17953(2010)
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Patino-Lopez, G., et al. J. Biol. Chem. 283(26):18323-18330(2008)
Hanono, A., et al. J. Cell Biol. 175(5):803-813(2006)
Itoh, T., et al. J. Biol. Chem. 281(42):31823-31831(2006)
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