|Application ||WB, E|
|Calculated MW||181796 Da|
|Antigen Region||928-955 aa|
|Other Names||182 kDa tankyrase-1-binding protein, TNKS1BP1, KIAA1741, TAB182|
|Target/Specificity||This TNKS1BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 928-955 amino acids from the Central region of human TNKS1BP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TNKS1BP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus. Cytoplasm, cytoskeleton. Chromosome. Note=Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin|
|Tissue Location||Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Tankyrase binding protein 1 binds to the ANK repeat domain of TNKS1 and TNKS2. There are 2 named isoforms produced by alternative splicing.
Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008)
Morita, M., et al. Mol. Cell. Biol. 27(13):4980-4990(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Gelmini, S., et al. Clin. Chem. Lab. Med. 45(7):862-866(2007)
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