TNKS1BP1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9C0C2 |
Other Accession | NP_203754.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 181796 Da |
Antigen Region | 928-955 aa |
Gene ID | 85456 |
---|---|
Other Names | 182 kDa tankyrase-1-binding protein, TNKS1BP1, KIAA1741, TAB182 |
Target/Specificity | This TNKS1BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 928-955 amino acids from the Central region of human TNKS1BP1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TNKS1BP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TNKS1BP1 |
---|---|
Synonyms | KIAA1741, TAB182 |
Cellular Location | Nucleus. Cytoplasm, cytoskeleton. Chromosome. Note=Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin |
Tissue Location | Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes |
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Provided below are standard protocols that you may find useful for product applications.
Background
Tankyrase binding protein 1 binds to the ANK repeat domain of TNKS1 and TNKS2. There are 2 named isoforms produced by alternative splicing.
References
Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008)
Morita, M., et al. Mol. Cell. Biol. 27(13):4980-4990(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Gelmini, S., et al. Clin. Chem. Lab. Med. 45(7):862-866(2007)
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