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TRMU Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TRMU Antibody (Center) AP19094C
    TRMU Antibody (Center) (Cat. #AP19094c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TRMU antibody detected the TRMU protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75648
Other Accession NP_060476.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47745 Da
Antigen Region 128-154 aa
Additional Information
Gene ID 55687
Other Names Mitochondrial tRNA-specific 2-thiouridylase 1, 281-, MTO2 homolog, TRMU, MTU1, TRMT1
Target/Specificity This TRMU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-154 amino acids from the Central region of human TRMU.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTRMU Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MTU1, TRMT1
Function Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2- thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.
Cellular Location Mitochondrion
Tissue Location Ubiquitous. Abundantly expressed in tissues with high metabolic rates including heart, liver, kidney, and brain.
Research Areas
Citations (0)

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This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.


Zeharia, A., et al. Am. J. Hum. Genet. 85(3):401-407(2009)
Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
de Moraes, V.C., et al. Biochem. Biophys. Res. Commun. 381(2):210-213(2009)
Otaegui, D., et al. Audiol. Neurootol. 13(5):320-327(2008)
Guan, M.X., et al. Am. J. Hum. Genet. 79(2):291-302(2006)

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$ 295.00
$ 99.00
Cat# AP19094C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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