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GPR39 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GPR39 Antibody (C-term) AP19112b
    GPR39 Antibody (C-term) (Cat. #AP19112b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GPR39 antibody detected the GPR39 protein (arrow).
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43194
Other Accession NP_001499.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51329 Da
Antigen Region 379-407 aa
Additional Information
Gene ID 2863
Other Names G-protein coupled receptor 39, GPR39
Target/Specificity This GPR39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-407 amino acids from the C-terminal region of human GPR39.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGPR39 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR39
Function Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in many tissues, including the stomach, intestine and hypothalamus.
Research Areas
Citations ( 0 )

Background

Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).

References

Sharir, H., et al. J. Biol. Chem. 285(34):26097-26106(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Holst, B., et al. J. Biol. Chem. 285(6):3973-3985(2010)
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Zhang, Y., et al. J. Endocrinol. 199(3):457-470(2008)

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$ 295.00
$ 99.00
Cat# AP19112b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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