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RXFP3 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RXFP3 Antibody (C-term) AP19132b
    RXFP3 Antibody (C-term) (Cat. #AP19132b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RXFP3 antibody detected the RXFP3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NSD7
Other Accession NP_057652.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 51124 Da
Antigen Region 404-432 aa
Additional Information
Gene ID 51289
Other Names Relaxin-3 receptor 1, RLN3 receptor 1, G protein-coupled receptor SALPR, G-protein coupled receptor GPCR135, Relaxin family peptide receptor 3, Somatostatin- and angiotensin-like peptide receptor, RXFP3, RLN3R1, SALPR
Target/Specificity This RXFP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human RXFP3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRXFP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RXFP3
Synonyms GPCR135, RLN3R1, SALPR
Function Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis
Research Areas
Citations (0)
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Background

RXFP3 is a receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.

References

Huang, Y.W., et al. Gynecol. Oncol. 117(2):239-247(2010)
van der Westhuizen, E.T., et al. Mol. Pharmacol. 77(5):759-772(2010)
Hossain, M.A., et al. Chem Biol Drug Des 73(1):46-52(2009)
Zhu, J., et al. Eur. J. Pharmacol. 590 (1-3), 43-52 (2008) :
Hossain, M.A., et al. J. Biol. Chem. 283(25):17287-17297(2008)

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$ 182.50
$ 70.00
Cat# AP19132b
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