|Application ||WB, E|
|Calculated MW||53179 Da|
|Antigen Region||184-213 aa|
|Other Names||Ammonium transporter Rh type C, Rh glycoprotein kidney, Rhesus blood group family type C glycoprotein, Rh family type C glycoprotein, Rh type C glycoprotein, Tumor-related protein DRC2, RHCG, C15orf6, CDRC2, PDRC2, RHGK|
|Target/Specificity||This RHCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-213 amino acids from the Central region of human RHCG.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHCG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C15orf6, CDRC2, PDRC2, RHGK|
|Function||Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.|
|Cellular Location||Apical cell membrane; Multi- pass membrane protein. Note=Also detected at the basolateral membrane and in subapical vesicles.|
|Tissue Location||Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney.|
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Provided below are standard protocols that you may find useful for product applications.
RHCG functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Gruswitz, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(21):9638-9643(2010)
Mouro-Chanteloup, I., et al. PLoS ONE 5 (1), E8921 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Han, K.H., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 297 (1), L153-L163 (2009) :
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